Vantage 6 ODBC Report Question

I added Tables to a existing Vantage Report via ODBC. The report will run in Crystal with no issues. But when I created the report style and added this report, then try and run the report inside Vantage I get a Error 599. I believe this error is due to a ODBC issue. The client machine running Vantage does have it's odbc connection setup. I tried modifying the vantage.mfg file to match my user/psw and server name that has ODBC but I stll get the Error 599 when I run the report. Does the appserver need to be restarted after modifying the .mfg file? Or is there something else?  Thanks for the help.