We had an issue with Avalara connectivity a couple years ago. Turned out to be a peice of IT equipment was re-deployed and was misconfigured. I could use tracert from my home ISP to Avalara and it would be just a few hops. But when I ran tracert on the App server, it would get to 30+ hops and timeout. Spent way to much time with Epicor and Avalar support when it wasn’t their fault.