Kinetic URL cache issue

Users who using our Kinetic URL to access our Epicor environment through Chrome instead of the local client are suddenly getting server error message (see below details) a couple times per day. If I open an incognito window when the error occurs, I can log into Epicor, other browsers load Epicor. I see no communications issues to the server.

We’ve been on Epicor going on 4 months now and this issue just started happening daily with all of our Epicor Chrome users. Local client Epicor users do not have this issue. The solution is to close all Chrome windows and reopen Chrome. I’ve cleared Chrome temp files and cache for all time.

I feel like this is an Epicor caching issue since the issue resolved when restarting chrome. Has anyone else experienced this and is there anything I can do from a cache management standpoint to prevent these issues?