Re-order quote lines

I know this has been asked before (a lot), and the solution is to make a new field for reference numbers for printing. It makes sense on how it would work technically, but I would like to know if anyone has implemented this in their business and how it ended up working for them not on a technical level, but on a business level. If everything in E-10 is based off of the originally assigned number, and I make a display number that is different, does it end up messing up the business when they have to cross reference these numbers? I could see that being a huge problem.