There have been some changes in this area over the course of Epicor 10.x, but, generally, if one updates the server’s clientdeployment .sysconfig files \\EpicorServerName\ERP[Release]Deployment\client\config\
during the next autoupdate the workstations that have the client installed would copy the changes made to the server’s copy to the local machine except for any settings in the local workstation’s <userSettings> block–they will not be overwritten by a setting in the server’s sysconfig file.